Nigeria : Hypertension treatment research programme enrols 23,000 patients, targets 5 new states

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By Felix Khanoba 

A collaborative academic research programme,  Hypertension Treatment in Nigeria, which has enrolled over 23,000 patients with the sickness, is seeking to scale up its work to five new states in Nigeria. 

Co-Principal Investigator, Hypertension Treatment in Nigeria programme, Professor Mark Huffman of the Washington University in St. Louis, USA, and Dike Ojji, associate professor and lead investigator, Cardiovascular Research Unit Department of Internal Medicine Faculty of Clinical Sciences, College of Health Sciences, University of Abuja, stated this at a recent stakeholders meeting in Abuja. 

They listed the five target states as Abia, Delta,  Gombe, Jigawa and Oyo. 

The Hypertension Treatment in Nigeria programme is a 5-year National Institutes of Health-funded  collaborative academic research work by the  University of Abuja, Washington University in Saint Louis, USA, and Northwestern University, Chicago, USA, which commenced in 2019, and is expected  to end in 2024. Other collaborators in this study are  Federal Ministry of Health of Nigeria, Resolve to Save Lives, World Health Organisation, Federal Capital Territory Primary Healthcare Board, and Public Health Department of Federal Capital Development Authority.

The research is ongoing in 60 primary healthcare centres in all the six area councils of the Federal Capital Territory (FCT). 

Giving an update on the project, Huffman and Ojji, who have been working on various research projects for some time, said, “We have submitted a renewal application to the NIH/NHLBI  to support national scale up in five states, and  diabetes integration in the FCT with support from other stakeholders.   

“If  approved, we are hopeful that it would have a significant effect on the treatment and care  of  hypertension, especially in Nigeria.” 

 Recall that hypertension is a leading cause of morbidity and mortality in Africa, and Nigeria, the most populous country on the continent, contributes significantly to this burden, with with high prevalence of over 30 percent. 

Huffman and Ojji’s team  is also working on a new study,  titled Enhancing Intergenerational Health in Nigeria: Peripartum as a Critical Life Stage for Cardiovascular Health (ENHANCE-CVH),  funded by NIH until  2028. This study focuses on maternal cardiovascular health and how it affects the newborn child.  

 The team, which also included Professor  Victor Davila-Roman of the Global Health Centre, Institute for Public Health, and Dr. Godwin Akaba of the University of Abuja, is  a collaborative academic research project between the University of Abuja and Washington University in Saint Louis, USA, in collaboration with Parents as Teachers, USA.

In a presentation, Dr. Ojji  said another important NIH funded work on which the team was focusing was the Nigeria Sodium Study, which commenced in 2020 and would end in 2026.

“The result is now driving the Front-of-Labelling of the Federal Ministry of Health,” Ojji said, adding that already the Federal  Ministry of Health had indicated interest to use the data from  this research to set nationwide limits on salt consumption, as a way of reducing cardiovascular diseases in the country.  

The  Nigerian Sodium Study Team  comprises Medical Scientists from University of Abuja, University of Abuja Teaching Hospital, Washington University in Saint Louis, Missouri, Northwestern University, Chicago; Nutrition Coordinating Centre, University of Minnesota; and the George Institute for Global Health; University of New South Wales, Australia, working in collaboration with the National Agency for Food Drug Administration and Control (NAFDAC), the Federal Ministry of Health (FMOH) Nigeria, Resolve to Save Lives (RTSL), and the Global Health Advocacy Incubator (GHAI).

The study is currently ongoing in the Federal Capital Territory of Nigeria, and two other states of Ogun and Kano, with the overall objective of establishing mandatory sodium limits in Nigerian food. 

” We believe that scaling up our studies,  collaborating with other important health institutions, and making the government come up with effective policies based on the results of cutting-edge health-related research will help improve our health system a lot,” Ojji said. 



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